Preliminary studies also showed adjunctive memantine improved a number of different attention-deficit/hyperactivity disorder (ADHD) measures.
#Take as needed for pain medical label series#
Two recent open-label case series suggest that the addition of memantine to standard medication therapy can benefit both children and adults with OCD. However, clomiphene has been studied in men dating back to the 1980s.Ī more recent 2007 study showed that 3 months of clomiphene treatment improved sperm count, motility, and morphology in men with a low sperm count.ĭue to increasing evidence of glutamate’s involvement in the pathophysiology of obsessive-compulsive disorder (OCD), some investigators have hypothesized that a drug modulating glutamate release, such as memantine, may be effective. Clomiphene (Clomid) for Male InfertilityĬlomiphene is approved for female infertility due to ovulatory disorder, so seeing the medication prescribed for men may raise some eyebrows.
Other non-FDA-approved uses for prazosin include the treatment of Raynaud’s disease and poisoning due to scorpion venom.Ģ. Prazosin is approved for the use of hypertension, but it is also used to treat nightmares related to post-traumatic stress disorder (PTSD).Ī 2012 systematic review showed a small but positive benefit of using prazosin for the treatment of PTSD-associated night terrors. Here is a list of 10 surprising off-label uses for prescription drugs: Most common among them were antidepressants, antipsychotics, and anticonvulsants. In the study, which was published in JAMA Internal Medicine, the rate of side effects for off-label drugs was 44% higher than on-label ones.Īlthough there is sometimes strong scientific evidence to support an off-label use, the study found that about 80% of the examined off-label prescriptions were not supported by strong scientific evidence. It is estimated that up to 20% of all medications prescribed are for indications that are not approved by the FDA. Off-label prescribing has been under scrutiny since a recent study found that medications prescribed for non-FDA-approved uses are associated with a significantly higher rate of negative side effects.
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